Acute heart failure is a big reason people go to the hospital and a major cause of death from heart disease in the US. It is known that chronic inflammatory diseases raise the risk of heart disease, but it is not clear how they affect the outcomes of acute heart failure.
An important new study from Alon Roguin, MD, and his colleagues at ACC.25 throws new light on this question. Researchers looked at 1,042,218 admissions linked to AHF from the National Inpatient Sample between 2016 and 2019. 39,485 of those people also had an inflammatory condition, like rheumatoid arthritis (RA), psoriasis, systemic lupus erythematosus (SLE), Crohn’s disease (CD), ulcerative colitis (UC), systemic scleroderma (SSc), Sjögren’s syndrome, or mixed connective tissue disease (MCTD).
It was a little older (72 years vs. 71 years) and more likely for women (67.8% vs. 47.0%) to have inflammatory diseases. Deaths in the hospital were about the same for both groups. However, individuals with inflammatory diseases experienced significantly more major adverse cardiovascular and cerebrovascular events and had longer hospital stays. Manhattan Cardiology’s Natalia Beridze, MD, agrees that an individual’s inflammatory status should influence their cardiovascular screening and management. Read the article.
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