Columbus Circle Location Is Now Open!
Manhattan Cardiology

When your heart is under stress, timely, specialized care can make all the difference. Our team at Manhattan Cardiology has extensive experience in diagnosing and managing rare, complex, and high-risk cardiac syndromes, whether they are acute or carry sudden risks. Below is a guide for patients explaining key conditions, symptoms to watch for, and how we approach diagnosis and treatment.

Understanding Acute & High-Risk Cardiac Conditions

Below is a patient-friendly overview of conditions we manage under our “Acute Cardiac” umbrella:

Electrical Disorders (Arrhythmogenic / Channelopathies)

Conditions that primarily affect the heart’s electrical system and rhythm.

  • Brugada Syndrome
  • Long QT Syndrome
  • WPW (Wolff-Parkinson-White) Syndrome

Structural / Myopathic Disorders

Conditions that primarily affect the heart muscle (myocardium) — its structure or function.

Inherited or Primary Cardiomyopathies

  • Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC)
  • Non-Compaction Cardiomyopathy
  • Dilated Cardiomyopathy
  • Hypertrophic Cardiomyopathy
  • Restrictive Cardiomyopathy

Acquired / Secondary Cardiomyopathies

  • Stress-Induced (Takotsubo) Cardiomyopathy
  • Amyloidosis (infiltrative cardiomyopathy)
  • Sarcoidosis (inflammatory/infiltrative cardiomyopathy)

Connective Tissue / Systemic Disorders Affecting the Heart

Conditions that primarily affect connective tissue or vascular integrity, with secondary cardiac effects.

  • Marfan’s Syndrome
  • Ehlers-Danlos Syndrome

Pericardial Disorders

Conditions involving the sac surrounding the heart.

  • Pericardial Effusion

Why Choose Us

At Manhattan Cardiology, your care is in the hands of highly trained specialists with extensive experience in treating complex heart conditions. Our physicians are:

  • Board-certified cardiologists with advanced training across subspecialties of cardiovascular medicine
  • Leaders in their field, with decades of combined experience diagnosing and managing rare and high-risk conditions
  • Active members of professional organizations such as the American College of Cardiology, ensuring they stay current with the latest guidelines and research
  • Recognized for their expertise in advanced imaging, electrophysiology, and preventive cardiology

In addition to their credentials, patients trust us for our commitment to accessible, comprehensive care:

  • Same-day appointments available for urgent needs
  • In-house diagnostic imaging and testing, so answers come quickly and efficiently
  • A patient-first approach where your questions are answered, and your treatment plan is tailored to your unique needs

With Manhattan Cardiology, you receive both the highest level of medical expertise and the convenience of care under one roof.

How We Work With You

  1. Initial Assessment & History
    We begin by taking a full medical and family history, including symptoms, prior tests, and any known genetic or systemic disease.
  2. Comprehensive Testing
    • ECG (resting, stress, special lead placements)
    • Echocardiography & Doppler
    • Cardiac MRI / CT / PET (as needed)
    • Electrophysiology study & intracardiac mapping
    • Genetic testing or biomarker studies
    • Biopsy or imaging of other organs (if systemic disease suspected)
  3. Personalized Treatment Plan
    Based on risk, severity, and comorbidities, we may recommend medications, lifestyle and activity guidance, catheter-based therapies (ablation), or device implantation (pacemaker/ICD).
  4. Close Follow-Up & Monitoring
    High-risk cardiac conditions require ongoing surveillance: remote monitoring, periodic imaging/ECG, and prompt adjustment of therapy.
  5. Patient Education & Shared Decision-Making
    We spend time helping you understand your condition, risks, and treatment options, so you feel confident in your care path.

Many of these conditions are rare, complex, and dangerous — but with the right experts and tools, outcomes improve. If your referring physician or the symptoms suggest an acute cardiac syndrome, Manhattan Cardiology is uniquely equipped to guide you through diagnosis and management.

Book an appointment today to begin your evaluation. Early detection and specialist care can save lives.

Meet Manhattan Cardiology

Jossef Amirian, M.D., F.A.C.C., F.A.S.E., C.B.N.C., R.P.V.I. is a compassionate and detail oriented Board Certified Cardiologist. Dr. Amirian is dedicated to the diagnosis and treatment of all aspects of cardiology with a particular interest in heart disease, preventative health, cardiovascular imaging and peripheral vascular disease.... Learn More »